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Synaptotagmin C2A Loop 2 Mediates Ca(2+)-dependent SNARE Interactions Essential for Ca(2+)-triggered Vesicle Exocytosis
Synaptotagmins contain tandem C2 domains and function as Ca(2+) sensors for vesicle exocytosis but the mechanism for coupling Ca(2+) rises to membrane fusion remains undefined. Synaptotagmins bind SNAREs, essential components of the membrane fusion machinery, but the role of these interactions in Ca...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096586/ https://ncbi.nlm.nih.gov/pubmed/17914059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0368 |
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