The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

Type 2 diabetes is characterized by the inability of insulin to suppress glucose production in the liver and kidney. Insulin inhibits glucose production by indirect and direct mechanisms. The latter result in transcriptional suppression of key gluconeogenetic and glycogenolytic enzymes, phosphoenolp...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Nakae, Jun, Kitamura, Tadahiro, Silver, David L., Accili, Domenico
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11696581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12876
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