Preserved Pancreatic β-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor

Receptors of the insulin/insulinlike growth factor (IGF) family have been implicated in the regulation of pancreatic β-cell growth and insulin secretion. The insulin receptor-related receptor (IRR) is an orphan receptor of the insulin receptor gene (Ir) subfamily. It is expressed at considerably hig...

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Detalhes bibliográficos
Main Authors: Kitamura, Tadahiro, Kido, Yoshiaki, Nef, Serge, Merenmies, Jussi, Parada, Luis F., Accili, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87283/
https://ncbi.nlm.nih.gov/pubmed/11463843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5624-5630.2001
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