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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

Type 2 diabetes is characterized by the inability of insulin to suppress glucose production in the liver and kidney. Insulin inhibits glucose production by indirect and direct mechanisms. The latter result in transcriptional suppression of key gluconeogenetic and glycogenolytic enzymes, phosphoenolp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nakae, Jun, Kitamura, Tadahiro, Silver, David L., Accili, Domenico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC209440/
https://ncbi.nlm.nih.gov/pubmed/11696581
Tagiau: Ychwanegu Tag
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