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Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor

Defective insulin secretion is a feature of type 2 diabetes that results from inadequate compensatory increase of β cell mass and impaired glucose-dependent insulin release. β cell proliferation and secretion are thought to be regulated by signaling through receptor tyrosine kinases. In this regard,...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Xuan, Shouhong, Kitamura, Tadahiro, Nakae, Jun, Politi, Katerina, Kido, Yoshiaki, Fisher, Peter E., Morroni, Manrico, Cinti, Saverio, White, Morris F., Herrera, Pedro L., Accili, Domenico, Efstratiadis, Argiris
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2002
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Article
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15276
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