Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor

Defective insulin secretion is a feature of type 2 diabetes that results from inadequate compensatory increase of β cell mass and impaired glucose-dependent insulin release. β cell proliferation and secretion are thought to be regulated by signaling through receptor tyrosine kinases. In this regard,...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Xuan, Shouhong, Kitamura, Tadahiro, Nakae, Jun, Politi, Katerina, Kido, Yoshiaki, Fisher, Peter E., Morroni, Manrico, Cinti, Saverio, White, Morris F., Herrera, Pedro L., Accili, Domenico, Efstratiadis, Argiris
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151144/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15276
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