Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation.
In liver, glucose utilization and lipid synthesis are inextricably intertwined. When glucose availability exceeds its utilization, lipogenesis increases, leading to increased intrahepatic lipid content and lipoprotein secretion. Although the fate of three-carbon metabolites is largely determined by...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Public Library of Science (PLoS)
2012-01-01
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| Ráidu: | PLoS ONE |
| Liŋkkat: | http://europepmc.org/articles/PMC3466224?pdf=render |
| Fáddágilkorat: |
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