Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal

Lignende værker

• The geometry of DNA supercoils modulates the DNA cleavage activity of human topoisomerase I
  af: Gentry, Amanda C., et al.
  Udgivet: (2011)
• Bimodal Recognition of DNA Geometry by Human Topoisomerase IIα: Preferential Relaxation of Positively Supercoiled DNA Requires Elements in the C-Terminal Domain
  af: McClendon, A. Kathleen, et al.
  Udgivet: (2008)
• Geometry of DNA Supercoils Modulates Topoisomerase-mediated DNA Cleavage and Enzyme Response to Anticancer Drugs
  af: McClendon, A. Kathleen, et al.
  Udgivet: (2006)
• ABILITY OF VIRAL TOPOISOMERASE II TO DISCERN THE HANDEDNESS OF SUPERCOILED DNA: BIMODAL RECOGNITION OF DNA GEOMETRY BY TYPE II ENZYMES
  af: McClendon, A. Kathleen, et al.
  Udgivet: (2006)
• Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities
  af: Tesauro, Cinzia, et al.
  Udgivet: (2020)