Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor

Severely elevated levels of total homocysteine (approximately millimolar) in the blood typify the childhood disease homocystinuria, whereas modest levels (tens of micromolar) are commonly found in adults who are at increased risk for vascular disease and stroke. Activation of the coagulation system...

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Autores principales: Lipton, Stuart A., Kim, Won-Ki, Choi, Yun-Beom, Kumar, Shanta, D’Emilia, Danielle M., Rayudu, Posina V., Arnelle, Derrick R., Stamler, Jonathan S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC20882/
https://ncbi.nlm.nih.gov/pubmed/9159176
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