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Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor

Severely elevated levels of total homocysteine (approximately millimolar) in the blood typify the childhood disease homocystinuria, whereas modest levels (tens of micromolar) are commonly found in adults who are at increased risk for vascular disease and stroke. Activation of the coagulation system...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lipton, Stuart A., Kim, Won-Ki, Choi, Yun-Beom, Kumar, Shanta, D’Emilia, Danielle M., Rayudu, Posina V., Arnelle, Derrick R., Stamler, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5923
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