Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor

Severely elevated levels of total homocysteine (approximately millimolar) in the blood typify the childhood disease homocystinuria, whereas modest levels (tens of micromolar) are commonly found in adults who are at increased risk for vascular disease and stroke. Activation of the coagulation system...

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Main Authors: Lipton, Stuart A., Kim, Won-Ki, Choi, Yun-Beom, Kumar, Shanta, D’Emilia, Danielle M., Rayudu, Posina V., Arnelle, Derrick R., Stamler, Jonathan S.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20882/
https://ncbi.nlm.nih.gov/pubmed/9159176
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