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N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro

Under defined culture conditions, exogenous glutamate (Glu), NMDA, or an endogenous Glu-related toxin is lethal to rat retinal ganglion cells; these detrimental effects are NMDA receptor mediated because specific NMDA antagonists can prevent cellular injury. In the presence of an endogenous Glu-like...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sucher, NJ, Aizenman, E, Lipton, SA
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575374/
https://ncbi.nlm.nih.gov/pubmed/1672708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-04-00966.1991
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