Učitavanje...
Protection of Retinal Ganglion Cells by Caspase Substrate-Binding Peptide IQACRG from N-Methyl-d-Aspartate Receptor-Mediated Excitotoxicity
PURPOSE. This study investigated whether the enzymatically inactive caspase mimetic IQACRG protects rat retinal ganglion cells (RGCs) from excitotoxic insults. Minimally invasive delivery of the peptide to the retina was explored, and the mechanisms of neuroprotection were elucidated. METHODS. IQACR...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868456/ https://ncbi.nlm.nih.gov/pubmed/19815732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4102 |
| Oznake: |
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