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Synthesis of the alkenyl-substituted tetracyclic core of the bisabosquals

HCl-catalyzed deprotection and cyclization of benzylic alcohol 15 cleanly provided tricycle 16 by a cis-selective intramolecular Diels-Alder reaction. Acetylation of the phenol, bis epoxidation, and base-catalyzed hydrolysis and cyclization afforded tetracycle 19 with the bisabosqual skeleton, but t...

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Detalhes bibliográficos
Main Authors: Zhou, Jingye, Lobera, Mercedes, Neubert-Langille, Bobbianna J., Snider, Barry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084385/
https://ncbi.nlm.nih.gov/pubmed/18836512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.07.033
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