Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death

Polyphosphate (polyP) consists of tens to hundreds of phosphates, linked by ATP-like high-energy bonds. Although polyP is present in mammalian mitochondria, its physiological roles there are obscure. Here, we examine the involvement of polyP in mitochondrial energy metabolism and ion transport. We c...

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Detalhes bibliográficos
Main Authors: Abramov, Andrey Y., Fraley, Cresson, Diao, Catherine T., Winkfein, Robert, Colicos, Michael A., Duchen, Michael R., French, Robert J., Pavlov, Evgeny
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084301/
https://ncbi.nlm.nih.gov/pubmed/17986607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708959104
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