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The Pore, not Cytoplasmic Domains, Underlies Inactivation in a Prokaryotic Sodium Channel

Kinetics and voltage dependence of inactivation of a prokaryotic voltage-gated sodium channel (NaChBac) were investigated in an effort to understand its molecular mechanism. NaChBac inactivation kinetics show strong, bell-shaped voltage dependence with characteristic time constants ranging from ∼50...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pavlov, Evgeny, Bladen, Christopher, Winkfein, Robert, Diao, Catherine, Dhaliwal, Perry, French, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366521/
https://ncbi.nlm.nih.gov/pubmed/15849254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056994
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