Trans-Channel Interactions in Batrachotoxin-Modified Skeletal Muscle Sodium Channels: Voltage-Dependent Block by Cytoplasmic Amines, and the Influence of μ-Conotoxin GIIIA Derivatives and Permeant Ions

External μ-conotoxins and internal amine blockers inhibit each other's block of voltage-gated sodium channels. We explore the basis of this interaction by measuring the shifts in voltage-dependence of channel inhibition by internal amines induced by two μ-conotoxin derivatives with different ch...

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Detalhes bibliográficos
Main Authors: Pavlov, Evgeny, Britvina, Tatiana, McArthur, Jeff R., Ma, Quanli, Sierralta, Iván, Zamponi, Gerald W., French, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Channels, Receptors, and Electrical Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567948/
https://ncbi.nlm.nih.gov/pubmed/18658222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.138297
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