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Docking of μ-Conotoxin GIIIA in the Sodium Channel Outer Vestibule
μ-Conotoxin GIIIA (μ-CTX) is a high-affinity ligand for the outer vestibule of selected isoforms of the voltage-gated Na(+) channel. The detailed bases for the toxin’s high affinity binding and isoform selectivity are unclear. The outer vestibule is lined by four pore-forming (P) loops, each with an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212855/ https://ncbi.nlm.nih.gov/pubmed/18690041 |
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