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Folding of noncoding RNAs during transcription facilitated by pausing-induced nonnative structures

RNA folding in the cell occurs during transcription. Expedient RNA folding must avoid the formation of undesirable structures as the nascent RNA emerges from the RNA polymerase. We show that efficient folding during transcription of three conserved noncoding RNAs from Escherichia coli, RNase P RNA,...

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Detalhes bibliográficos
Main Authors: Wong, Terrence N., Sosnick, Tobin R., Pan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084285/
https://ncbi.nlm.nih.gov/pubmed/17986617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705038104
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