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Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similar

Experimental and computational folding studies of Proteins L & G and NuG2 typically find that sequence differences determine which of the two hairpins is formed in the transition state ensemble (TSE). However, our recent work on Protein L finds that its TSE contains both hairpins, compelling a r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Baxa, Michael C., Yu, Wookyung, Adhikari, Aashish N., Ge, Liang, Xia, Zhen, Zhou, Ruhong, Freed, Karl F., Sosnick, Tobin R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500205/
https://ncbi.nlm.nih.gov/pubmed/26100906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503613112
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