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Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange

The relationship between folding cooperativity and downhill, or barrier-free, folding of proteins under highly stabilizing conditions remains an unresolved topic, especially for proteins such as λ-repressor that fold on the microsecond timescale. Under aqueous conditions where downhill folding is mo...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Yu, Wookyung, Baxa, Michael C., Gagnon, Isabelle, Freed, Karl F., Sosnick, Tobin R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855600/
https://ncbi.nlm.nih.gov/pubmed/27078098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522500113
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