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Distributivity and Processivity in Multisite Phosphorylation Can Be Distinguished through Steady-State Invariants

Multisite protein phosphorylation and dephosphorylation are key cellular regulatory mechanisms but their system properties have been difficult to study in vivo and in vitro. Here we show by mathematical analysis that steady-state invariants enable the mechanism of the kinase or the phosphatase to be...

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Sonraí Bibleagrafaíochta
Príomhúdar: Gunawardena, Jeremy
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084251/
https://ncbi.nlm.nih.gov/pubmed/17704153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.110866
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