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Multisite Phosphorylation and Network Dynamics of Cyclin-Dependent Kinase Signaling in the Eukaryotic Cell Cycle
Multisite phosphorylation of regulatory proteins has been proposed to underlie ultrasensitive responses required to generate nontrivial dynamics in complex biological signaling networks. We used a random search strategy to analyze the role of multisite phosphorylation of key proteins regulating cycl...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Biophysical Society
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304250/ https://ncbi.nlm.nih.gov/pubmed/15189845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.036558 |
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