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Hysteresis and Cell Cycle Transitions: How Crucial Is It?

Recently, experiments have shown that cyclin-dependent kinase (CDK) activity exhibits hysteresis in its response to total cyclin when cyclin is made nondegradable and controlled externally. This observation was taken to support mathematical modeling predictions regarding the underlying dynamics of t...

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Detalhes bibliográficos
Main Authors: Han, Zhangang, Yang, Ling, MacLellan, W. Robb, Weiss, James N., Qu, Zhilin
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305219/
https://ncbi.nlm.nih.gov/pubmed/15626707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053066
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