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Hysteresis and Cell Cycle Transitions: How Crucial Is It?

Recently, experiments have shown that cyclin-dependent kinase (CDK) activity exhibits hysteresis in its response to total cyclin when cyclin is made nondegradable and controlled externally. This observation was taken to support mathematical modeling predictions regarding the underlying dynamics of t...

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Autors principals: Han, Zhangang, Yang, Ling, MacLellan, W. Robb, Weiss, James N., Qu, Zhilin
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305219/
https://ncbi.nlm.nih.gov/pubmed/15626707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053066
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