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The Geometry of Multisite Phosphorylation

Reversible protein phosphorylation on multiple sites is a key regulatory mechanism in most cellular processes. We consider here a kinase-phosphatase-substrate system with two sites, under mass-action kinetics, with no restrictions on the order of phosphorylation or dephosphorylation. We show that th...

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Detalhes bibliográficos
Main Authors: Manrai, Arjun Kumar, Gunawardena, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599844/
https://ncbi.nlm.nih.gov/pubmed/18849417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.140632
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