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Distributivity and Processivity in Multisite Phosphorylation Can Be Distinguished through Steady-State Invariants
Multisite protein phosphorylation and dephosphorylation are key cellular regulatory mechanisms but their system properties have been difficult to study in vivo and in vitro. Here we show by mathematical analysis that steady-state invariants enable the mechanism of the kinase or the phosphatase to be...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084251/ https://ncbi.nlm.nih.gov/pubmed/17704153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.110866 |
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