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A Conserved Role for Phosphoinositide-3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy
Physiological cardiac hypertrophy is associated with mitochondrial adaptations that are characterized by activation of PGC-1α and increased fatty acid oxidative (FAO) capacity. It is widely accepted that phosphoinositide-3 Kinase (PI3K) signaling to Akt1 is required for physiological cardiac growth....
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084219/ https://ncbi.nlm.nih.gov/pubmed/17908558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.09.001 |
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