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A Conserved Role for Phosphoinositide-3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy

Physiological cardiac hypertrophy is associated with mitochondrial adaptations that are characterized by activation of PGC-1α and increased fatty acid oxidative (FAO) capacity. It is widely accepted that phosphoinositide-3 Kinase (PI3K) signaling to Akt1 is required for physiological cardiac growth....

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Xehetasun bibliografikoak
Egile Nagusiak: O’Neill, Brian T., Kim, Jaetaek, Wende, Adam R., Theobald, Heather A., Tuinei, Joseph, Buchanan, Jonathan, Guo, Aili, Zaha, Vlad G., Davis, Don K., Schell, John C., Boudina, Sihem, Wayment, Benjamin, Litwin, Sheldon E., Shioi, Tetsuo, Izumo, Seigo, Birnbaum, Morris J., Abel, E. Dale
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084219/
https://ncbi.nlm.nih.gov/pubmed/17908558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.09.001
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