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The conserved phosphoinositide 3-kinase pathway determines heart size in mice
Phosphoinositide 3-kinase (PI3K) has been shown to regulate cell and organ size in Drosophila, but the role of PI3K in vertebrates in vivo is not well understood. To examine the role of PI3K in intact mammalian tissue, we have created and characterized transgenic mice expressing constitutively activ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212739/ https://ncbi.nlm.nih.gov/pubmed/10835352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2537 |
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