The conserved phosphoinositide 3-kinase pathway determines heart size in mice

Phosphoinositide 3-kinase (PI3K) has been shown to regulate cell and organ size in Drosophila, but the role of PI3K in vertebrates in vivo is not well understood. To examine the role of PI3K in intact mammalian tissue, we have created and characterized transgenic mice expressing constitutively activ...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Shioi, Tetsuo, Kang, Peter M., Douglas, Pamela S., Hampe, James, Yballe, Claudine M., Lawitts, Joel, Cantley, Lewis C., Izumo, Seigo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2000
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10835352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.11.2537
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