Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses

Pathological cardiac hypertrophy may be associated with reduced expression of glucose transporter 4 (GLUT4) in contrast to exercise-induced cardiac hypertrophy, where GLUT4 levels are increased. However, mice with cardiac-specific deletion of GLUT4 (G4H(−/−)) have normal cardiac function in the unst...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Wende, Adam R., Kim, Jaetaek, Holland, William L., Wayment, Benjamin E., O’Neill, Brian T., Tuinei, Joseph, Brahma, Manoja K., Pepin, Mark E., McCrory, Mark A., Luptak, Ivan, Halade, Ganesh V., Litwin, Sheldon E., Abel, E. Dale
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814656/
https://ncbi.nlm.nih.gov/pubmed/28822962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00101.2017
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