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Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases
In eukaryotes, shortening of the 3′-poly(A) tail is the rate-limiting step in the degradation of most mRNAs, and two major mRNA deadenylase complexes—Caf1–Ccr4 and Pan2–Pan3—play central roles in this process, referred to as deadenylation. However, the molecular mechanism triggering deadenylation re...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cold Spring Harbor Laboratory Press
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2081979/ https://ncbi.nlm.nih.gov/pubmed/18056425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1597707 |
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