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PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores

The spindle checkpoint delays anaphase onset until every chromosome kinetochore has been efficiently captured by the mitotic spindle microtubules. In this study, we report that the human pre–messenger RNA processing 4 (PRP4) protein kinase associates with kinetochores during mitosis. PRP4 depletion...

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Bibliografiske detaljer
Main Authors: Montembault, Emilie, Dutertre, Stéphanie, Prigent, Claude, Giet, Régis
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080909/
https://ncbi.nlm.nih.gov/pubmed/17998396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703133
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