ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores

To prevent genome instability, mitotic exit is delayed until all chromosomes are properly attached to the mitotic spindle by the spindle assembly checkpoint (SAC). In this study, we characterized the function of ARHGEF17, identified in a genome-wide RNA interference screen for human mitosis genes. T...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Isokane, Mayumi, Walter, Thomas, Mahen, Robert, Nijmeijer, Bianca, Hériché, Jean-Karim, Miura, Kota, Maffini, Stefano, Ivanov, Miroslav Penchev, Kitajima, Tomoya S., Peters, Jan-Michael, Ellenberg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792069/
https://ncbi.nlm.nih.gov/pubmed/26953350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408089
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