ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores

To prevent genome instability, mitotic exit is delayed until all chromosomes are properly attached to the mitotic spindle by the spindle assembly checkpoint (SAC). In this study, we characterized the function of ARHGEF17, identified in a genome-wide RNA interference screen for human mitosis genes. T...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Isokane, Mayumi, Walter, Thomas, Mahen, Robert, Nijmeijer, Bianca, Hériché, Jean-Karim, Miura, Kota, Maffini, Stefano, Ivanov, Miroslav Penchev, Kitajima, Tomoya S., Peters, Jan-Michael, Ellenberg, Jan
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792069/
https://ncbi.nlm.nih.gov/pubmed/26953350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408089
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