ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores

To prevent genome instability, mitotic exit is delayed until all chromosomes are properly attached to the mitotic spindle by the spindle assembly checkpoint (SAC). In this study, we characterized the function of ARHGEF17, identified in a genome-wide RNA interference screen for human mitosis genes. T...

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Vydáno v:J Cell Biol
Hlavní autoři: Isokane, Mayumi, Walter, Thomas, Mahen, Robert, Nijmeijer, Bianca, Hériché, Jean-Karim, Miura, Kota, Maffini, Stefano, Ivanov, Miroslav Penchev, Kitajima, Tomoya S., Peters, Jan-Michael, Ellenberg, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792069/
https://ncbi.nlm.nih.gov/pubmed/26953350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408089
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