ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores

To prevent genome instability, mitotic exit is delayed until all chromosomes are properly attached to the mitotic spindle by the spindle assembly checkpoint (SAC). In this study, we characterized the function of ARHGEF17, identified in a genome-wide RNA interference screen for human mitosis genes. T...

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Библиографические подробности
Опубликовано в: :J Cell Biol
Главные авторы: Isokane, Mayumi, Walter, Thomas, Mahen, Robert, Nijmeijer, Bianca, Hériché, Jean-Karim, Miura, Kota, Maffini, Stefano, Ivanov, Miroslav Penchev, Kitajima, Tomoya S., Peters, Jan-Michael, Ellenberg, Jan
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2016
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792069/
https://ncbi.nlm.nih.gov/pubmed/26953350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408089
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