Aggregation of Expanded Polyglutamine Domain in Yeast Leads to Defects in Endocytosis

The role of aggregation of abnormal proteins in cellular toxicity is of general importance for understanding many neurological disorders. Here, using a yeast model, we demonstrate that mutations in many proteins involved in endocytosis and actin function dramatically enhance the toxic effect of poly...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Meriin, Anatoli B., Zhang, Xiaoqian, Miliaras, Nicholas B., Kazantsev, Alex, Chernoff, Yury O., McCaffery, J. Michael, Wendland, Beverly, Sherman, Michael Y.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2003
Materias:	Cell Growth and Development
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7554-7565.2003
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