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Synergism between hypersensitive sites confers long-range gene activation by the β-globin locus control region

The human β-globin locus control region (LCR) consists of four erythroid-specific DNaseI hypersensitive sites (HSs) at the 5′ end of the β-globin cluster. The LCR functions over a long distance on chromosome 11 to regulate transcription and replication of the β-globin genes. To determine whether the...

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Detalhes bibliográficos
Main Authors: Bresnick, Emery H., Tze, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20763/
https://ncbi.nlm.nih.gov/pubmed/9114030
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