Synergism between hypersensitive sites confers long-range gene activation by the β-globin locus control region
The human β-globin locus control region (LCR) consists of four erythroid-specific DNaseI hypersensitive sites (HSs) at the 5′ end of the β-globin cluster. The LCR functions over a long distance on chromosome 11 to regulate transcription and replication of the β-globin genes. To determine whether the...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4566 |
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