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Synergism between hypersensitive sites confers long-range gene activation by the β-globin locus control region
The human β-globin locus control region (LCR) consists of four erythroid-specific DNaseI hypersensitive sites (HSs) at the 5′ end of the β-globin cluster. The LCR functions over a long distance on chromosome 11 to regulate transcription and replication of the β-globin genes. To determine whether the...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The National Academy of Sciences of the USA
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20763/ https://ncbi.nlm.nih.gov/pubmed/9114030 |
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