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Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists
Nod2 (CARD15) is a macrophage-specific protein containing two CARD domains, a large nucleotide binding domain and leucine-rich repeats. Human genetic studies have linked mutations in NOD2/CARD15 with Crohn's disease, although the mechanisms involved are unknown. However, Nod2 has been proposed...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC207570/ https://ncbi.nlm.nih.gov/pubmed/14560001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7531-7539.2003 |
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