Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

Nod2 (CARD15) is a macrophage-specific protein containing two CARD domains, a large nucleotide binding domain and leucine-rich repeats. Human genetic studies have linked mutations in NOD2/CARD15 with Crohn's disease, although the mechanisms involved are unknown. However, Nod2 has been proposed...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pauleau, Anne-Laure, Murray, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC207570/
https://ncbi.nlm.nih.gov/pubmed/14560001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7531-7539.2003
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares