Toll-like Receptor Agonists Promote Prolonged Triglyceride Storage in Macrophages

Macrophages in infected tissues may sense microbial molecules that significantly alter their metabolism. In a seeming paradox, these critical host defense cells often respond by increasing glucose catabolism while simultaneously storing fatty acids (FA) as triglycerides (TAG) in lipid droplets. We u...

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Main Authors: Huang, Ying-ling, Morales-Rosado, Joel, Ray, Jessica, Myers, Timothy G., Kho, Terry, Lu, Mingfang, Munford, Robert S.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Lipids
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908431/
https://ncbi.nlm.nih.gov/pubmed/24337578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524587
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