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Prolonged Triglyceride Storage in Macrophages: pH(o) trumps pO(2) and TLR4
Lipid-laden macrophages contribute to pathologies as diverse as atherosclerosis and tuberculosis. Three common stimuli are known to promote macrophage lipid storage: low tissue oxygen tension (pO(2)), low extracellular pH (pH(o)), and exposure to agonists such as bacterial lipopolysaccharide (LPS)....
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108542/ https://ncbi.nlm.nih.gov/pubmed/24973452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400886 |
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