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Differential expression of the topoisomerase II alpha and beta genes in human breast cancers.

Topoisomerase II is a key target for several anti-cancer drugs used for breast cancer therapy, including doxorubicin, epirubicin and mitoxantrone. Two isoforms of topoisomerase II (alpha and beta) have been described in human cells which differ in their subcellular localisation, biochemical properti...

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Autori principali: Sandri, M. I., Hochhauser, D., Ayton, P., Camplejohn, R. C., Whitehouse, R., Turley, H., Gatter, K., Hickson, I. D., Harris, A. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074549/
https://ncbi.nlm.nih.gov/pubmed/8664122
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