Differential expression of the topoisomerase II alpha and beta genes in human breast cancers.

Topoisomerase II is a key target for several anti-cancer drugs used for breast cancer therapy, including doxorubicin, epirubicin and mitoxantrone. Two isoforms of topoisomerase II (alpha and beta) have been described in human cells which differ in their subcellular localisation, biochemical properti...

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Hlavní autoři: Sandri, M. I., Hochhauser, D., Ayton, P., Camplejohn, R. C., Whitehouse, R., Turley, H., Gatter, K., Hickson, I. D., Harris, A. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1996
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074549/
https://ncbi.nlm.nih.gov/pubmed/8664122
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