Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.

DNA topoisomerase II is a nuclear enzyme essential for chromosome dynamics and DNA metabolism. In mammalian cells, two genetically and biochemically distinct topoisomerase II forms exist, which are designated topoisomerase II alpha and topoisomerase II beta. In our studies of human topoisomerase II,...

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Detalhes bibliográficos
Main Authors: Biersack, H, Jensen, S, Gromova, I, Nielsen, I S, Westergaard, O, Andersen, A H
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38663/
https://ncbi.nlm.nih.gov/pubmed/8710863
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