Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24.

Topoisomerases catalyse the interconversion of topological isomers of DNA and have key roles in nucleic acid metabolism. Human cells express two distinct type II topoisomerase isozymes, designated topoisomerase II alpha (170 kDa form) and topoisomerase II beta (180 kDa form). We have isolated cDNA c...

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Autores principales: Jenkins, J R, Ayton, P, Jones, T, Davies, S L, Simmons, D L, Harris, A L, Sheer, D, Hickson, I D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC334390/
https://ncbi.nlm.nih.gov/pubmed/1333583
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