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The disulfide relay system of mitochondria is connected to the respiratory chain

All proteins of the intermembrane space of mitochondria are encoded by nuclear genes and synthesized in the cytosol. Many of these proteins lack presequences but are imported into mitochondria in an oxidation-driven process that relies on the activity of Mia40 and Erv1. Both factors form a disulfide...

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Bibliographic Details
Main Authors: Bihlmaier, Karl, Mesecke, Nikola, Terziyska, Nadia, Bien, Melanie, Hell, Kai, Herrmann, Johannes M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064786/
https://ncbi.nlm.nih.gov/pubmed/17967948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707123
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