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Mitochondrial Disulfide Relay: Redox-regulated Protein Import into the Intermembrane Space

99% of all mitochondrial proteins are synthesized in the cytosol, from where they are imported into mitochondria. In contrast to matrix proteins, many proteins of the intermembrane space (IMS) lack presequences and are imported in an oxidation-driven reaction by the mitochondrial disulfide relay. In...

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Autors principals: Herrmann, Johannes M., Riemer, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281597/
https://ncbi.nlm.nih.gov/pubmed/22157015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.270678
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