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Mitochondrial Disulfide Relay: Redox-regulated Protein Import into the Intermembrane Space

99% of all mitochondrial proteins are synthesized in the cytosol, from where they are imported into mitochondria. In contrast to matrix proteins, many proteins of the intermembrane space (IMS) lack presequences and are imported in an oxidation-driven reaction by the mitochondrial disulfide relay. In...

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Bibliographic Details
Main Authors: Herrmann, Johannes M., Riemer, Jan
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281597/
https://ncbi.nlm.nih.gov/pubmed/22157015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.270678
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