Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells

Oxidation of cysteine residues to disulfides drives import of many proteins into the intermembrane space of mitochondria. Recent studies in yeast unraveled the basic principles of mitochondrial protein oxidation, but the kinetics under physiological conditions is unknown. We developed assays to foll...

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Main Authors: Fischer, Manuel, Horn, Sebastian, Belkacemi, Anouar, Kojer, Kerstin, Petrungaro, Carmelina, Habich, Markus, Ali, Muna, Küttner, Victoria, Bien, Melanie, Kauff, Frank, Dengjel, Jörn, Herrmann, Johannes M., Riemer, Jan
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708723/
https://ncbi.nlm.nih.gov/pubmed/23676665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-12-0862
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