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Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria
m-AAA proteases exert dual functions in the mitochondrial inner membrane: they mediate the processing of specific regulatory proteins and ensure protein quality control degrading misfolded polypeptides to peptides. Loss of these activities leads to neuronal cell death in several neurodegenerative di...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155303/ https://ncbi.nlm.nih.gov/pubmed/21610694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.169 |
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